Clinical Dbservation of the Curative Effect of Metoprolol and Shengmai Capsule in Treating Chronic Renal Failure and Chronic Heart Failure
Abstract:ObjectiveTo evaluate the efficacy and safety profile of metoprolol and Shengmaimai capsule in chronic renal failure(CRF) and chronic heart failure(CHF).Methods52 cases patients with CRF and CHF were divided into treatment group (27 cases) and control group(25 cases). All the patients were followed up for months and measured respectively the changes of heart rate(HR), blood puessure(BP) and cardiac function by the colur Dopper ECE.Results48 patients completed the treatment.The LVEDD, LVESD, heart function and symptoms were improved in both groups while the treatment group was more obvious than the control group(P<0.05).The result of HR and BP decreased significantly after treatemt comparatively(P<0.05), while the HR in the treatment decreased more obvious than the control group (P<0.01),but there was no significant difference in HR(P>0.05).ConclusionOn the basis of routine therapy metoyrolol and Shengmaimai capsule can improve the symptoms and heart function significantly in patients with CRF and CHF. Most of patients are able to endure therapy.
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