Abstract:ObjectiveTo prepare and determine the content and entrapment efficiency of Hydroquinone liposome.MethodsHydroquinone liposome was prepared by evaporating and ultrasound method, determined the concentration and the entrapment efficiency of Hydroquinone liposome by HPLC. ResultsHydroquinone had a good linear relationship in a range of 5.0 ~50.0 μg/ml. The entrapment efficiency of Hydroquinone liposome in three groups reached 83.26%, 89.13%, 80.75% respectively.ConclusionThe technology of preparing Hydroquinone liposome was feasible and the method of quality control was simple and accurate.