Abstract:ObjectiveTo observe the effects of total extracts of Yexiazhu on nervous system,cardiovascular system,and respiratory system in mice and dogs.MethodsThe times of freedom movement in mice ,the effect on the hypnotic dosage and subthreshold hypnotic dosage of Pentobarbital Sodium in mice,the blood pressure, heart rates in dogs were observed.ResultsThe blood pressure,heart beat rate,heart rhythm,respiratory rate,depth of respiration ,freedom movement,hypnotic dosage and subthreshold hypnotic dosage of pentobarbital Sodium in animals had no obvious difference after given total extracts of Yexiazhu.ConclusionTotal extracts of Yexiazhu in effective dose have no obvious influence on nervous system in mice,respiratory system and cardiovascular system in dogs.