Abstract:ObjectiveTo study the anti-inflammatory and analgesic effect of FuguiGutong Capsule(FGC).MethodsAnti-inflammatory effect of FGC was studied with the model of egg white induced swelling in rat paw and of dye exudation induced by acetic acid. Using the pain model in mice induced by acetic and hot plate, the analgesic effect of FGC was investigated.Results FGC (60,200 mg·kg-1)significantly reduced the degree of the swelling induced by egg white in rat, and FGC (100,300 mg·kg-1)inhibited the dye exudation induced by acetic acid in mice, which indicated its anti-inflammatory its effect. FGC (20,600.mg·kg-1) obviously decreased the number of rats, lifting paws. The number of writhe induced by acetic acid decreased significanlty and the pain threshold of temperature stimuli increased markedly in mice when administrated with FGC (100,300 mg·kg-1); FGC (300 mg·kg-1) also prolonged the latency of writhe.ConclusionFGC has obvious anti-inflammatory and analygesic effects.