Abstract:ObjectiveTo research the extraction process of the Compound Houttuynia Oral Liquid. MethodsVolatile oils which are active ingredients of the medicinal materials were extracted by steam distillation method; water-soluble components which are active ingredients were extracted by boiling methods, optimized by orthogonal test and determined by TLC - UV spectrophotometry.ResultsThe optimum technological conditions for extracting volatile oil were as follows:the ratio of water to sample was 10:1,the time of warm-infusion was 0.5R,Steam distillation time was 4 h;the water soluble constituents were extracted with water(10 times of the materials) for 2 times,two hours each time.ConclusionThe method is simple and feasible, can be used as the extraction process of the Compound Houttuynia Oral Liquid.